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Almost complete pain relief with Metformin


#1

I held off sharing this with the group until I was certain it was a durable pain response.

As many of you know I’ve had lingering issues for the last 5 1/2 years after my reversal. I was able to go back to work after reversal as it took care of the worst of my pain but still could get issues with prolonged sitting.

I am not diabetic. My fasting sugar was getting close to pre-diabetic so I had discussed Metformin with my doctor last year. This year I started having trouble with stubborn weight despite vigorous exercise and training so I requested a script for Metformin to see if it could help me lose some weight.

I started on 500mg a day on a Wednesday and by Saturday when I was expecting to have my usual end of week soreness and pain it never came or was very mild. I figured it was the Metformin and looked online and sure enough there is medical data/research on the use of metformin for neuropathic pain.

It’s been almost 3 months now and I don’t really think about or worry about pain anymore. I still have some altered sensation in my scrotum at my incision sites and where I was dissected/reconnected and my balls of course hang a little higher/different but absent pain I am okay with it.

I want to emphasize that this result was both totally unexpected and has been very dramatic.

I’ll post one of the many links I found about Metformin for pain relief. Again, I did not start taking it expecting any benefit at all in the area of pain management.


#2

Glad to hear it Mike :+1:


#3

That sounds amazing Mike. I will try it.
Thanks for sharing


#4

Very Interesting! Thanks for sharing.
Any side effects and if so, how do you handle them?


#5

@chronic_pain,

The one side effect is it makes me tired. When I was training for a swim meet this fall I felt like it made it harder for me to train without getting fatigued so I stopped for a 2 weeks until after my meet and then started up again after my meet.

I take the XR version.

The first night after I took it I did not sleep hardly at all but that went away quickly.

As far as the fatigue goes I feel like that has gotten a little better but I think that may just be unique to me as well. I think the main complaint most people have with it is gastro-intestinal issues. The XR version supposedly takes care of that complaint for most and that’s what I’m on.

I figure for many guys having nerve pain type soreness and discomfort this might be a good thing to try. It may be hard getting a script for it however since it is an off-label use.

It is a cheap old and safe drug and I think it’s something anyone considering surgery should look into. I certainly wish I had been able to try it before my reversal. You want to fire every bullet you can before resorting to surgery. I feel we encourage all men to take that approach and most guys do exhaust the conservative measures first but it’s worth restating.


#6

Has this helped with your arthritis type pain and body soreness?


#7

Not really. I’m 52. When I exert myself I get inflammation and pain in my joints/body.

One thing I’ve noticed though is that if I have a big day of work if I fast while I’m working I don’t get nearly as much of that type of pain. If I get up in the morning and start tackling a task in the yard or garage, the longer I can go without eating the less I have issues with stiffening up.

Fasting is a good way to turn off inflammation for me.

It’s no fun but it works.

If I come in and have a big meal after 5 hours or so of working and sit down for a few minutes, forget. I’m the tin man.


#8

#9

Guys, I am going to pin this for a few weeks to make sure folks see it. I have had remarkable relief since I started taking Metformin.


#10

Hi @MikeO, glad to hear this brings you relief!!! I feel with everyone on this site and every success story brings hope to people out here suffering and looking for a relief.
Can you tell what type of pain you mostly had ?


#11

I had some burning and paresthesia in my groin around where I was dissected (origianal vas) and reconnected (vas reversal). I had scrotal pain where I was in the scrotum basically. I had some pain lower to toward the perineum. It was nerve type pain, not really that testicular type of aching (except a little on the right side).

I had dramatic reduction after about 4 days on metformin. I don’t even have to take it every day. I usually take it at least 5 days during a week. The reason I don’t take it every day is it can make me tired. A couple days off and I’m fine.

I have no idea how it works but in the article I listed you can see that there is awareness in the medical community of its ability to modulate chronic pain/pain perception.

I would like to try ketamine as well but I’m doing good on just metformin right now. It’s night and day.


#12

Good to hear that’s working for you Mike! I’ll keep this in mind if my pain starts to come back